Below I will briefly introduce the effects of jujube and costus root porridge, I hope it will be of some help to you. Jujube and Aucklandia CongeeThe effect of jujube and aucklandia porridge1. Effects on the gastrointestinal tract: The extract of costus root, volatile oil and total alkaloids first had a mild excitatory effect on the isolated small intestine of rats, and then the tension and rhythmicity decreased significantly. The extract of costus root can significantly enhance the amplitude of intestinal peristalsis and intestinal muscle tension of isolated rabbits; it has an antagonistic effect on intestinal muscle spasms caused by Ach, histamine and BaCl2. Large doses of decoction, volatile oil, volatile oil without lactone, total lactone, and various lactone parts such as costus root lactone and dihydrocostus root lactone all have an inhibitory effect on the movement of isolated rabbit small intestine. The total alkaloids can also antagonize the spasm caused by Ach and histamine on the isolated guinea pig ileum. The volatile oil without lactone, dihydrocostus root lactone and total lactone can significantly inhibit the movement of large and small intestines in vivo, reduce their tension and rhythmic contraction, and other lactone parts have less effect. Cloud costus root alkaloids have a significant inhibitory effect on the isolated small intestine of rabbits and cats, and intravenous injection can also significantly inhibit the movement of the small intestine of cats in vivo, relax the intestinal muscles, stop the movement, but recover easily. The effect of jujube and aucklandia porridge2. Effects on the cardiovascular system:Low concentrations of volatile oils and the lactone fractions separated from volatile oils have different degrees of inhibitory effects on the isolated hearts of various animals. Small doses of water extracts and alcohol extracts can excite frog hearts and dog hearts in vivo, while large doses have inhibitory effects. Intravenous injection of costusin has an excitatory effect on cat hearts in vivo. Delactone volatile oils, total lactones, and 12-methoxy-dihydrocostus lactone can increase the perfusion volume of isolated rabbit ears and rat hind limb blood vessels, and have a more obvious vasodilation effect. Small doses of total alkaloids can dilate isolated rabbit ear blood vessels, while large doses can cause contraction reactions. Intravenous injection of delactone volatile oils, total lactones, costus lactones, dihydrocostus lactones, dehydrocostus lactones, and 12-methoxy-dihydrocostus lactone can moderately reduce the blood pressure of anesthetized dogs, and the antihypertensive effect is relatively long-lasting. The three benefits of jujube and aucklandia porridge3. Effects on the respiratory system:The extract, alcohol extract, volatile oil and total alkaloids of Yunmuxiang can counteract the spasmodic effect of histamine and Ach on the bronchi in vitro. The lactone components such as total lactone, costus lactone, dihydrocostus lactone and delactone volatile oil contained in the volatile oil can counteract the bronchoconstriction caused by histamine, Ach and BaCl2, among which dihydrocostus lactone is more effective. Intraperitoneal injection of Yunmuxiang total lactone, costus lactone, dihydrocostus lactone or delactone volatile oil has a protective effect on guinea pigs that inhale lethal doses of histamine or Ach aerosol, can prolong the incubation period of asthma and reduce the mortality rate. Intravenous injection of Yunmuxiang alkaloids can cause bronchial dilation in anesthetized cats. Intravenous injection of water extract, alcohol extract, volatile oil, volatile oil without lactone and total alkaloids had a certain inhibitory effect on the respiration of anesthetized dogs, slowing down the frequency and reducing the amplitude, among which volatile oil had the strongest effect. The effect of jujube and aucklandia porridge4. Anti-pathogenic microorganisms:Volatile oil can inhibit the growth of streptococci, golden yellow and white Staphylococci, and has a weak effect on Escherichia coli and diphtheria. Yunmuxiang decoction has an inhibitory effect on 10 fungi such as Trichophyton thunbergii and its Mongolian variant, and has a slight inhibitory effect on Paratyphoid Salmonella. Yunmuxiang also has an inhibitory effect on bovine tuberculosis and human tuberculosis. The efficacy of jujube and aucklandia porridge5. Other functions:Oral administration of ethanol extract of Aucklandia lappa can reduce blood sugar in rats. Aucklandia lappa lactone has cytotoxic effect on human nasopharyngeal carcinoma cells. |
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