The efficacy of placenta porridge

1. Anti-infection effect: Placental γ-globulin contains antibodies such as measles and influenza, as well as diphtheria antitoxin, which can be used to prevent or alleviate infectious diseases such as measles. Because it is a protein, oral administration is ineffective and must be injected. Placental γ-globulin also contains interferon, which can be used clinically to prevent or control viral infections. The placenta also contains lysozyme, which can prevent the death of mice (intraperitoneal injection) caused by endotoxins of Salmonella enteritidis, Salmonella typhimurium, and Shigella flexneri; it also has a certain protective effect on the damage of endotoxins to rats; but it has no effect on endotoxemia caused by Escherichia coli.

2. Enhance the body's resistance: Oral administration of placenta powder to mice can reduce their tuberculosis lesions, and in test tubes it can promote the growth of tuberculosis bacteria, so it is believed that its main function is to increase the body's resistance. The hydrochloric acid hydrolysis product of the defatted placenta, injected intraperitoneally into rats, has a significant inhibitory effect on liver fat deposition caused by carbon tetrachloride and ethylthiobutyric acid (Ethionin). Subcutaneous injection of human placenta extract into mice can prolong their swimming time; intramuscular injection into rats has a certain preventive and therapeutic effect on experimental gastric ulcers of certain experimental types (reserpine, tension, ligation of the lower part of the pylorus, etc.).

3. Hormone-like effects: The placenta can physiologically produce chorionic gonadotropin, which has little effect on the ovaries, but has an excitatory effect on the testicles; in addition, it can also produce estrogen and progesterone. The placenta may contain these hormones, and therefore has the pharmacological effects of these hormones. Chorionic gonadotropin is a protein substance, which is ineffective when taken orally and requires injection. Injection of placental extract into lactating rabbits seems to promote their development, and can significantly promote the development of the thymus, spleen, uterus, vagina, mammary glands, etc. It also has a promoting effect on the thyroid gland, testicles, etc., and has almost no effect on the pituitary gland, adrenal glands, ovaries, pancreas, liver, kidneys, etc.

4. Effect on blood coagulation: The placenta contains the so-called urokinase inhibitor, which can inhibit the activation of urokinase on plasminogen; this can explain the decrease in fibrinolytic activity during pregnancy. According to measurements, the ratio of plasminogen activator to urokinase inhibitor in the myometrium during pregnancy is 1:3.4, while the ratio of the two in the placenta is as high as 1:1197. The human placenta contains low molecular weight coagulation factor XII (a glycoprotein), so it can be used to treat bleeding patients due to factor XII deficiency. This coagulation factor can not only stabilize fibrin clots and promote wound healing, but also has an anti-histamine effect in animal experiments.

5. Other effects: In in vitro experiments, placental extracts can promote the recovery of suppressed hearts. Placental proteins contain renin-like pressor substances, and their significance in regulating blood circulation needs to be further clarified. Human placenta also contains a certain glycoprotein component, which can inhibit the synthesis of DNA in lymphocytes in in vitro experiments, but does not affect the vitality of cells. Placental extracts can inhibit the fever caused by methamphetamine in large quantities. The pepsin digestion fluid, water extract and 70% acetone extract of refrigerated placenta were measured with a Valsalva respirator, which can promote the respiration of several tissues such as the liver, heart, and brain, as well as the respiration of yeast. The refrigerated ones have a stronger effect than the non-refrigerated ones. Placental serum has an excitatory effect on the isolated guinea pig uterus, similar to the posterior pituitary hormone. The intradermal reaction of placental chorionic villus extract in cancer patients is more significant than that in healthy people, and has a certain diagnostic value. It can be further studied to improve its specificity. Estrogen-like effects: The placenta contains a variety of enzyme systems that are involved in the metabolism of steroid hormones, such as estrogen and progesterone; the placenta also secretes chorionic gonadotropin, which has the function of promoting the development of breasts and female reproductive organs.