The efficacy of rice porridge

1. Anti-tumor effect:

1.1. Intraperitoneal injection of coix seed ethanol extract into tumor-bearing mice can inhibit the proliferation of Ehrlich ascites carcinoma (ECA) cells and significantly prolong the survival time of the animals. Two components further separated from the extract, one of which can cause protoplasmic degeneration of cancer cells, and the other component can stop the division phase of the cell nucleus at the midphase.

1.2. The acetone extract of coix seed can also inhibit the growth of ECA when injected intraperitoneally into mice. This anti-tumor activity can be transferred to the acidic part soluble in petroleum ether. If it is injected subcutaneously, the ascites becomes transparent and the tumor cells almost disappear. However, the toxicity of this part is also relatively high. The acetone extract of coix seed also has a significant inhibitory effect on cervical cancer 14 (U14) and ascites type liver cancer (HCA) solid tumors.

1.3. Clinical application of the decoction of coix seed can be observed to prolong the life of patients with advanced cancer. It was found that after intraperitoneal injection of coix seed acetone extract into cancer patients, the protoplasm of cancer cells was significantly degenerated through ascites examination. It was also found that 50% ethanol extract of coix seed can promote the keratinization of cultured squamous cell carcinoma cells.

The effect of rice porridge

Immune effects

2.1. The neutral polysaccharide glucan mixture and the acidic polysaccharide Ⅱa-1, 2, 3, and Ⅱb parts obtained from the hot water extract of coix seed all showed anti-complement activity.

2.2. The neutral polysaccharide dextran mixture is highly heterogeneous and can be separated into seven dextran species by HPLC. They are 1→4-linked aD-dextrans containing glucosyl side chains at positions 0-6 of the main chain. Each purified dextran has a different maximum absorption (530nm or >550nm) in the iodine reaction. >500nm-dextran is more effective than 530nm-dextran and is believed to have considerable anti-complement activity.

2.3. Acidic polysaccharides Ⅱa-1, 2, 3, Ⅱb were further separated and purified to obtain anti-complement polysaccharides CA-1 and CA-2, which contained 8-11% protein and had molecular weights of 160,000 and 70,000, respectively. At low doses, CA-2 showed stronger anti-complement activity than CA-1.